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Also, growth hormone levels drop as we get older, and there was interest in seeing if tweaking these levels might benefit older adults struggling with loss of bone and muscle mass and increases in body fat

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A modified mutant human NNMT (mt-hNNMT) [lacking 3 amino acid residues from the C-terminus of the NNMT protein that was not observed in crystal structure] (3ROD, PDB accession code) cloned into an IPTG-inducible plasmid pJ401 expression vector was purchased from DNA 2.0 (Menlo Park, Calif.)