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The durability of vaccine protection is another key area that requires a better understanding of the fundamentals of immune memory, a key question being “ how can we limit the acute contraction of the adaptive immune response after prophylactic vaccination and limit attrition of long-term memory , in particular for nAb titers in the blood?”

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The prevalence of AD ranges from 10–20% in childhood to 2–8% in adulthood and the main manifestations are itching and eczematous lesions in particularly in the flexural areas (1–3)

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