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co-packaged covalent organic frameworks (COFs) with the chemotherapeutic drug cis-aconityl-doxorubicin (CAD) prodrug and heptamethine dye IR783 to form nanocomposites (COF@IR783@CAD), overcoming the limitations of low dispersion and water stability of COFs, prolonging the blood circulation time, and realizing the synergy of PTT and chemotherapy (Wang et al., 2019)
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