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Frontiers | Pichia pastoris secreted peptides crossing the blood-brain barrier and DSIP fusion peptide efficacy in PCPA-induced insomnia mouse models

However, there is not enough conclusive evidence to confirm whether DNA hypomethylation due to folate or B12 deficiency is a direct causal factor in the development of CRC

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Colitis-associated cancer research: A 2016 study found that KPV reduced tumor development in a murine model of colitis-associated colon cancer, suggesting that its ability to dampen chronic gut inflammation may interrupt the inflammation-to-cancer progression that drives some colorectal cancers