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Electron microscopic analysis of FTD and amyotrophic lateral sclerosis patients with TDP43 pathology revealed prominent mitochondrial impairment, including abnormal and/or depleted cristae, concordant with ultrastructural changes observed in both cellular and animal models of TDP43 proteinopathy (Wang et al., 2019)
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doi: 10.1016/j.jhazmat.2018.07.059 69 KhanM.SiddiquiZ
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