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Why oral absorption fails, since it is not a formulation problem that better capsules would fix: the same study reports the compound is highly soluble — over 100 mg/mL in phosphate-buffered saline and over 10 mg/mL in simulated gastric fluid — and barely binds plasma protein (7%)
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Understanding these symptoms can guide individuals towards considering Vitamin B12 injections to boost energy and alleviate deficiency symptoms
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