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S-(1,2,2-trichlorovinyl)-L-cysteine sulfoxide, a reactive metabolite of S-(1,2,2-Trichlorovinyl)-L-cysteine formed in rat liver and kidney microsomes, is a potent nephrotoxicant

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Unfortunately, however, in the case of glutamate, the event did not involve discovery of a new treatment but instead the discovery of two closely related compounds-phencyclidine (PCP) and ketamine-that produced symptoms and cognitive deficits in healthy volunteers that closely resembled those of schizophrenia