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[oai_citation:1‡PubMed]( 2) Nitric-oxide–mediated, largely endothelium-dependent vasorelaxation Aortic ring experiments showed vasodilation that was blunted by L-NAME and hemoglobin and attenuated without endothelium—consistent with NO-mediated effects

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3.1.2 Indole-3-acetic acid (IAA) Indole-3-acetic acid (IAA), another protein-bound toxin, is also a product of tryptophan metabolism by gut microbiota