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101 Finally, a general argumentation within the commonly accepted concepts, holds that the wound healing process accomplished all of the four major events (vascular constriction, loose platelet plug, fibrin mesh to ensure stability of platelet plug, dissolution of the clot) that occur in a set order following the loss of vascular integrity

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Therefore, there is currently no unified cutoff directly applicable for clinical diagnosis or classification, nor are there fully validated sensitivity, specificity, and dynamic range