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Animal studies have demonstrated that aortic banding upregulates cardiac NOX4 expression and suppresses GPX4 activity [47,48], while SLC7A11 deficiency exacerbates angiotensin II-induced cardiac hypertrophy and fibrosis [49]
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Many commercial formulations lack standardisation, and product labelling often fails to accurately reflect cannabinoid content or purity, leading to diminished consumer trust and increased regulatory concerns
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