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A more recent study using advanced MRI to quantify regional BBB integrity further reveals that BBB dysfunction is an early event in aging brain, which starts from the hippocampus and may contribute to cognitive impairment (Montagne et al., 2015)

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We propose that nebulization of 3000 mg per day of NAC or GSH may suffice in controlling the aggravation of oxidative stress and inflammation arising from the severe cytokine storm in pulmonary structures (Fig