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Figure 3 3.3 Δ BacA induce higher secretion of pro-inflammatory cytokines in mice serum Blood samples were collected from each mouse 3 weeks after inoculation
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Reduced peri-infarct astrocyte reactivity in C3a-treated mice was associated with upregulation of Igf1 and Thbs4 , coding for insulin-like growth factor 1 (IGF-1) and thrombospondin-4 (THBS4), respectively, both of which are highly expressed in peri-infarct astrocytes 383
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