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DAMPs released by dying hepatocytes, along with PAMPs, stimulate Kupffer cells to upregulate proinflammatory cytokines, leading to the recruitment of neutrophils and macrophages to the liver [40, 41]
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During maturation, NEUs generate three distinct types of granules: primary granules, which contain enzymes such as myeloperoxidase (MPO) and neutrophil elastase (NE)
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