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Introduction to the pentose phosphate pathway The pentose phosphate pathway (PPP) also known as the hexose monophosphate shunt or phosphogluconate pathway, branches from glycolysis at the first committed step, which is catalyzed by hexokinase and consumes glucose-6-phosphate as a primary substrate (Fig

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The ecosystem harbored inside the intestine results damaged and, consequently, this increases inflammation (by bacterial components as described) and neuroinflammation, by neuroactive compounds (even from microbial metabolism) and other neuromodulatory mechanisms, as explained below